PBGV Health & Rescue Research Projects


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ACTIVE

CHF 02133: Improving the fate of dogs who have epilepsy; University of Minnesota; Ned E. Patterson, DVM PhD; Start 10-1-2014; Active
Canine Epilepsy: Genetic Variants, Biomarkers, and New Therapies. Learn More

CHF 02145-A: What causes primary closed angle glaucoma? Animal Health Trust; Dr. Cathryn S Mellersh, Ph.D.; Start 11-1-2014; Active
Prevention of Glaucoma and Goniodysgenesis through Genetic Profiling of Disease. Learn More
End-Year 1 (Final) 10-31-2015

CHF 02103-A: Prevention of Periodontal Disease; Boston Medical Center; Dr. Paola Massari, PhD; Start 11-1-2014; Active
Development of an Effective Canine Periodontal Disease Vaccine. Learn More

CHF 02011 Treatment for Cushing's; University of Utrecht; Sara Galac, DVM PhD; Start 1-1-2014; Active
Identification of Novel Drugs to Halt the Metastasis of Tumors That Cause Cushing's Syndrome. Learn More
End of Year 1, 12-31-2014

CHF 2002 Cause of Inflammatory Bowel Disease; University of London; Karin Allenspach, DVM PhD; Start 1-1-2014; Active
Defining the Genetic Basis of Inflammatory Bowel Disease Learn More

CHF 01995 How dogs learn; Duke University; Evan MacLean, PhD; Start 1-1-2014; Active
Understanding the Flexibility and Limitations of How Dogs Acquire Knowledge and Understanding: Application to Service Dog Emotional Health and Selection Learn More
End of Year 12-31-2014
End of Year 2 12-31-2015

CHF 1904-A Ehrlichia prevalence study; University of Tennessee; Rebecca Trout Fryxel, PhD; Start 1-1-2013; Active
Documentation of Disease-Causing Ticks in a Field Trial Environment for the Purpose of Developing Practical and Cost-Effective Strategies for Tick Control. Learn More

CHF 1894 Documentation of Disease-Causing Ticks in a Field Trial Environment for the Purpose of Developing Practical and Cost-Effective Strategies for Tick Control
End of Year 1 (FINAL) 1-31-2014

CHF 1893-A Test of dextrose as treatment for arthritis; Kansas State University; James Roush, DVM; Start 11-1-2013; Active
A Novel, Practical, and Cost-Effective Treatment for Canine Arthritis. Learn More
Mid-Year 2 4-30-2013

CHF 1699-A Diagnosis of Brucellosis; University of Minnesota, Christina Larson, DVM; Start 3-1-2013; Active
Preventing Inaccurate Diagnosis of Brucellosis. Learn More

CHF 1609 Probiotic treatment for inflammatory bowel disease; Iowa State University, E. Jergens, DVM, PhD; Partially funded by PBGV HRF; Start 1-1-2012; Active
Probiotic VSL# 3 Reduces Enteritis in Dogs with Inflammatory Bowel Disease.
CHF description

Year 1 midyear Report CHF End Year 1 (4/4/2013)
End Year 1 (12/2012)
Year 2 midyear report, June 2013
Year 2 midyear Summary, June 2013

ARCHIVE

CHF 1896-A Melatonin as an anti-seizure drug; Washington State University; Stephanie Thomovsky, DVM; Start 7-1-2013; Close 12-31-2014
A Pilot Study: Establishing the Role of Melatonin in the Occurrence of Seizures in Dogs. Learn More
Final Report, 12-31-2014

CHF 1612 Cyclosporin A treatment for cataract surgery; Ohio State University; Heather Chandler, PhD; partically funded by PBGV HRF; start 1-1-2012; Complete
Modified Cyclosporin A to Improve Cataract Surgery Outcomes.
CHF description

Year 1 midyear report Feb 2013
Year 2, midyear report, June 2013
Final Report, 6/30/13

CHF 1594 Identification of glaucoma disease gene; University of Iowa; Markus H. Kuehn, PhD; partially funded by PBGV HRF; Start 1-1-2012; Complete 12-31-2013
Analysis of Familial Glaucoma in the Basset Hound.
CHF description

Year 1 midyear report Feb 2013
CHF End Year 1(1/16/2012)
End Year 1 (12/2012)
Final Report; 1/3/2014

CHF 1265 Autoimmune; Universtiy of Wollongong, Australia; Ronald Sluyter, PhD; partially funded by PBGV HRF; Start 2010; Complete
Understanding Mechanisms Involved in Canine Autoimmune & Inflammatory Disorders
CHF Description
Local Description
Year 1 Report
Year 2 final report FINAL

CHF 1497A Pancreatic Insufficiency; Clemson University, SC; Leigh Anne Clark, PhD; partially funded by PBGV HRF; Start 2010; Complete
Dog Leukocyte Antigen 88 Typing in German Shepherd Dogs Having Pancreatic Insufficiency
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Report Posted 1-17-12
Final Report, Sept 2011

CHF 762 Epilepsy; University of Missouri; Gary S. Johnson, DVM, PhD; partially funded by PBGV HRF; Start 2010; Complete
The Mapping and Characterization of Canine Epilepsy Loci
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CHF 1099 Infectious agents associated with meningoencephalitis; University of Georgia; Scott Schatzberg, DVM, PhD; partially funded by PBGV HRF; Start 2009; Complete
Degenerate PCR for Detection of Viral, Bacterial, and Rickettsial Genera in Pugs and Maltese Dogs with Necrotizing and Granulomatous Meningoencephalitis
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Final Year 2 Report

CHF 1227A Pancreatitis testing; University of California, Davis; Stanely L. Marks, BVSc, PhD; partially funded by PBGV HRF; Start 2009; Complete
Specificity and Sensitivity of the Pancreatic Lipase Immunoreactivity (SPEC cPL) Test for the Diagnosis of Canine Pancreatitis
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CHF 747 Canine glaucoma; University of Missouri; Elizabeth A. Giuliano, DVM, MS, DACVO; partially fund by PBGV HRF; Start 2008; Complete Oct 97 to Sep 10
The Mapping and Characterization of Mutations Responsible for Canine Glaucoma
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End of Year 2 Report

CHF 1113 Role of cancer stem cells in lymphoma; University of Minnesota, Timothy D. O'Brien, DVM, PhD; partially funded by PBGV HRF; Start 2008; Complete
Canine Non-Hodgkin Lymphoma: Characterization and Prognostic Value of Cancer Stem Cells
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Report
10/ 2011 Report

CHF 1147 Hemangiosarcoma; Tufts University; Chieko Azuma, DVM, PhD; partially funded by PBGV HRF; Start 2008; Complete
Identifying Mutations in Genes Associated with Canine Hemangiosarcoma
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CHF 762 Epilepsy; University of Missouri; Gary S. Johnson, DVM, PhD; partially funded by PBGVCA; Start 2008; Complete
The Mapping and Characterization of Canine Epilepsy Loci
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CHF 779 Male dog infertility; Texas A&M; William J. Murphy, PhD; partially funded by PBGV HRF; Start 2007; Complete
Characterization of the Canine Y Chromosome: Identifying Genes that Cause Male Infertility
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CHF 759 Vaccine Reactions; Purdue; George Moore, DVM; partially funded by PBGV HRF; Start 2007; Complete
Investigation of Antigenetic Causes of Vaccine-Associated Allergic Reactions in Dogs
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CHF 593A Hemangiosarcoma; Broad Institute; Kerstin Lindblad-Toh, PhD; partially fund by PBGV HRF; Start 2007; Complete
Mapping Genes Associated with Canine Hemangiosarcoma
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CHF 305 Immune disease including diabetes; University of Utah; Wayne Potts, PhD; partially funded by PBGVV HRF; Start 2004; Complete
Histocompatibility Alleles Conferring Susceptibility to Canine Diabetes, Immune Medicated Thyroiditis and Immune-Mediated Hemolytic Anemia
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CHF 2434 Thyroid testing; University of Georgia; Duncan Ferguson, DVM, PhD; partially funded by PBGV HRF; Start 2003; Complete
Recombinant Thyrotropin (TSH): Standard for the Next Generation of Canine TSH Immunoassays with Improved Sensitivity
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CHF 2291 Lens luxation and glaucoma; University of Missouri; Gary S. Johnson, DVM, PhD; partially funded by PBGV HRF; Start 2002; Complete
Canine Lens Luxation and Glaucoma Research Project
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